Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.51 |
| ▸ | PPARG | P37231 | 18/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503845 | 0.88 | PPARG (0.58) | PPARAPPARG | |
| SCHEMBL11729032 | 0.83 | PPARA (0.56) | PPARAPPARG | |
| SCHEMBL1628567 | 0.82 | GAA (0.47) | PPARAPPARGHPGDMEN1CYP1A2 | |
| SCHEMBL5914738 | 0.81 | TPMT (0.38) | PPARAPPARG | |
| SCHEMBL11112713 | 0.81 | LDHA (0.45) | PPARAPPARG | |
| SCHEMBL10880775 | 0.79 | ALDH1A3 (0.55) | PPARAPPARGCYP1A2CYP2C19KMT2A | |
| SCHEMBL7867822 | 0.79 | PPARG (0.54) | PPARAPPARG | |
| SCHEMBL11641221 | 0.79 | PPARG (0.61) | PPARAPPARG | |
| SCHEMBL11728381 | 0.79 | PPARA (0.64) | PPARAPPARG | |
| SCHEMBL5925159 | 0.78 | PPARG (0.59) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |