Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7028923 | 0.75 | ALDH1A1 (0.70) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL6351827 | 0.74 | FERMT2 (0.41) | FERMT2SYK | |
| SCHEMBL6313654 | 0.73 | ALDH1A1 (0.59) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL1928147 | 0.72 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL15757422 | 0.72 | MTNR1A (0.60) | FERMT2SYKPOLB | |
| SCHEMBL444746 | 0.72 | PDGFRB (0.58) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL27787646 | 0.71 | TAAR1 (0.47) | FERMT2ALDH1A1SYKPOLB | |
| SCHEMBL3018368 | 0.71 | GAA (0.76) | FERMT2ALDH1A1APPPPARGKDM4E | |
| SCHEMBL434861 | 0.71 | PDGFRB (0.59) | PDGFRBPDGFRAALDH1A1F2GLA | |
| SCHEMBL1069903 | 0.71 | KDM4E (0.43) | FERMT2SYKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997006161-A1 | ANTICOCCIDIAL 8-AMINOQUINOLINE DERIVATIVES | PFIZER LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |