Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.60 |
| ▸ | THRB | P10828 | 8/20 | 0.60 |
| ▸ | THRA | P10827 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3228615 | 0.92 | THRB (0.51) | RORCTHRBTHRA | |
| SCHEMBL8893208 | 0.90 | THRB (0.47) | RORCTHRBTHRA | |
| SCHEMBL8891842 | 0.88 | THRA (0.66) | THRBTHRA | |
| SCHEMBL8890840 | 0.86 | THRB (0.46) | RORCTHRBTHRA | |
| SCHEMBL3221887 | 0.84 | RORC (0.54) | RORCTHRBTHRA | |
| SCHEMBL3221253 | 0.84 | POLB (0.48) | THRBTHRA | |
| SCHEMBL3703144 | 0.82 | RORC (0.52) | RORCTHRBTHRA | |
| SCHEMBL3783634 | 0.82 | THRB (0.46) | RORCTHRBTHRA | |
| SCHEMBL6368421 | 0.82 | RORC (0.64) | RORCTHRBTHRA | |
| SCHEMBL3221894 | 0.82 | RORC (0.58) | RORCTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654468-A | ANTILIPID, ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5569674-A | ANTICHOLESTEROL AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| US-5401772-A | Anticholesterol agents with aromatic amines | CIBA-GEIGY CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |