Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP2CA | P67775 | 7/20 | 0.80 |
| ▸ | PPP5C | P53041 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.66 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.58 |
| ▸ | PTPA | Q15257 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL889307 | 0.95 | PPP2CA (0.89) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15381940 | 0.94 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444945 | 0.94 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15444944 | 0.94 | PPP2CA (0.90) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL889288 | 0.91 | PPP2CA (0.80) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL889228 | 0.90 | PPP2CA (0.80) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL823120 | 0.90 | PPP2CA (0.80) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL820205 | 0.90 | PPP2CA (0.80) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15445017 | 0.89 | PPP2CA (1.00) | PPP2CAPPP5CALDH1A1THRBHPGD | |
| SCHEMBL15445018 | 0.89 | PPP2CA (1.00) | PPP2CAPPP5CALDH1A1THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010282-A1 | Tautomycetin and Tautomycetin Analog Biosynthesis | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010282-A1 | Tautomycetin and Tautomycetin Analog Biosynthesis | COASY, TTN, TKT | PPP2CA 813/4885PPP5C 569/4885ALDH1A1 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.