Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CETP | P11597 | 3/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781675 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL12802756 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL9775285 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL28034249 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL28034352 | 1.00 | SIGMAR1 (0.51) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL27753131 | 0.98 | SIGMAR1 (0.53) | SIGMAR1CETPHRASHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL7870266 | 0.91 | SIGMAR1 (0.44) | SIGMAR1CETPHRASHPGDMEN1 | |
| SCHEMBL437919 | 0.91 | MAOA (0.48) | SIGMAR1HRAS | |
| SCHEMBL1240611 | 0.85 | HRAS (0.46) | SIGMAR1HRASALDH1A1 | |
| SCHEMBL8863637 | 0.82 | MAOA (0.47) | SIGMAR1HRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696964-A | HEAT RESISTANCE, OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | claimed |
| US-5618793-A | ANTIFUNGAL AGENT | SCHERING CORPORATION (US) | 1997-04-08 | — | — | US | disclosed |
| US-5346898-A | FOR TREATING FUNGAL INFECTIONS IN MAMMALS | SCHERING CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5236900-A | Treating Candida infections | SCHERING CORPORATION (US) | 1993-08-17 | — | — | US | disclosed |
| US-4696964-A | HEAT RESISTANCE, OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1987-09-29 | — | — | US | disclosed |