SCHEMBL8893112

SCHEMBL8893112

Cc1ncc(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)o1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
HSP90AA1 P07900 1/20 0.52
CXCR5 P32302 1/20 0.52
APLNR P35414 1/20 0.52
RAB9A P51151 1/20 0.52
CCR6 P51684 1/20 0.52
GFER P55789 1/20 0.52
TLR9 Q9NR96 1/20 0.48
AGTR1 P30556 1/20 0.47
CA1 P00915 6/20 0.44
CA2 P00918 6/20 0.44
CA12 O43570 5/20 0.44
CA9 Q16790 5/20 0.44
CA14 Q9ULX7 4/20 0.44
CA3 P07451 3/20 0.44
CA4 P22748 3/20 0.44
CA6 P23280 3/20 0.44
CA5A P35218 3/20 0.44
CA7 P43166 3/20 0.44
CA13 Q8N1Q1 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8891249 0.79 TSHR (0.50) KMT2ACA1CA2CA12CA9
SCHEMBL25106807 0.74 KMT2A (0.59) KMT2AHSP90AA1CXCR5APLNRRAB9A
SCHEMBL11151582 0.74 MAPT (0.60) KMT2ARAB9ACA1CA2CA12
SCHEMBL15690970 0.74 KMT2A (0.55) KMT2AHSP90AA1CXCR5APLNRRAB9A
SCHEMBL11419996 0.73 CA2 (0.67) KMT2AAGTR1CA1CA2CA12
SCHEMBL3158508 0.73 CA2 (0.67) KMT2AAGTR1CA1CA2CA12
SCHEMBL11855965 0.73 CA2 (0.67) KMT2AAGTR1CA1CA2CA12
SCHEMBL6577803 0.72 ACHE (0.75) KMT2AHSP90AA1CXCR5APLNRRAB9A
SCHEMBL20379626 0.72 HSP90AA1 (0.83) KMT2AHSP90AA1CXCR5APLNRRAB9A
Dimethylamine SCHEMBL11150939 0.71 MAPT (0.56) KMT2ARAB9ACA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997024340-A1 OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-07-10 WO disclosed