SCHEMBL11855965

SCHEMBL11855965

O=[N+]([O-])c1ccc(S(=O)(=O)c2ccc(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.67
CA1 P00915 7/20 0.67
CA9 Q16790 6/20 0.67
CA12 O43570 5/20 0.67
CA14 Q9ULX7 4/20 0.67
CA3 P07451 3/20 0.67
CA4 P22748 3/20 0.67
CA6 P23280 3/20 0.67
CA5A P35218 3/20 0.67
CA7 P43166 3/20 0.67
CA13 Q8N1Q1 3/20 0.67
CA5B Q9Y2D0 3/20 0.67
KMT2A Q03164 2/20 0.61
POLB P06746 1/20 0.61
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP13 P45452 1/20 0.59
GAA P10253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419996 1.00 CA2 (0.67) CA2CA1CA9CA12CA14
SCHEMBL3158508 1.00 CA2 (0.67) CA2CA1CA9CA12CA14
SCHEMBL10451887 0.93 CA1 (0.70) CA2CA1CA9CA12CA14
SCHEMBL11854911 0.93 CA1 (0.70) CA2CA1CA9CA12CA14
SCHEMBL11655146 0.91 AGTR1 (0.64) CA2CA1CA9CA12CA14
SCHEMBL3895943 0.91 AGTR1 (0.64) CA2CA1CA9CA12CA14
SCHEMBL9136918 0.89 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL6577803 0.89 ACHE (0.75) CA2CA1CA9CA12CA14
SCHEMBL2762326 0.89 ALDH1A1 (0.75) CA2CA1CA9CA12CA14
SCHEMBL6038264 0.89 HSPB1 (0.60) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3947480-A Dinitro- and diamino arylene disulfones UNIROYAL, INC. (US) 1976-03-30 US disclosed