Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899495 | 0.78 | POLB (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL8893140 | 0.68 | MAPT (0.34) | HPGDSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL8899509 | 0.66 | GAA (0.33) | SMN1; SMN2MAPTGAANPSR1 | |
| SCHEMBL8890049 | 0.65 | GAA (0.41) | HPGDSMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL8890215 | 0.64 | MAPT (0.35) | HPGDKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL12425622 | 0.61 | HPGD (0.51) | HPGDUSP2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5154526 | 0.61 | — | — | |
| SCHEMBL31582281 | 0.60 | POLB (0.72) | HPGDSMN1; SMN2KDM4ELMNAALDH1A1 | |
| SCHEMBL24778821 | 0.59 | HPGD (0.50) | HPGDUSP2SMN1; SMN2KDM4ELMNA | |
| SCHEMBL615361 | 0.59 | MCL1 (0.59) | HPGDUSP2SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |