Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28570167 | 0.83 | ALDH1A1 (0.53) | POLBNR1H4MAPTKDM4EALDH1A1 | |
| SCHEMBL17659123 | 0.81 | DRD2 (0.51) | POLBDRD2DRD4DRD3DRD1 | |
| SCHEMBL19403575 | 0.80 | ALDH1A1 (0.67) | POLBNR1H4MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14922275 | 0.79 | POLB (0.71) | POLBDRD2DRD4DRD3MAPT | |
| SCHEMBL6981569 | 0.79 | MAPT (0.60) | POLBDRD2DRD4DRD3DRD1 | |
| SCHEMBL4101709 | 0.79 | HTR3A (0.59) | NR1H4DRD2DRD3DRD1HTR2A | |
| Bromide SCHEMBL27463561 | 0.77 | HTR3A (0.58) | NR1H4DRD2DRD3DRD1HTR2A | |
| Bromide SCHEMBL6772862 | 0.77 | HTR3A (0.58) | NR1H4DRD2DRD3DRD1HTR2A | |
| SCHEMBL24309509 | 0.76 | HSP90AA1 (0.54) | POLBDRD2DRD4DRD3DRD1 | |
| SCHEMBL18295995 | 0.76 | DRD2 (0.56) | POLBDRD2DRD4DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |