Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968757 | 0.87 | POLB (0.52) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL3906341 | 0.86 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL1118771 | 0.80 | TRPM8 (0.56) | KDM4ETRPM8HPGDPOLBKMT2A | |
| SCHEMBL11540415 | 0.79 | CES2 (0.48) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL12669562 | 0.77 | KDM4E (0.55) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL13367406 | 0.75 | MEN1 (0.54) | KDM4ENPC1SMN1; SMN2TRPM8BLM | |
| SCHEMBL31098975 | 0.74 | KDM4E (0.52) | KDM4ENPC1RAB9ASMN1; SMN2PKM | |
| SCHEMBL7978882 | 0.72 | TP53 (0.49) | NPC1RAB9APKMTRPM8CDK5 | |
| SCHEMBL13338802 | 0.72 | KDM4E (0.53) | KDM4ESMN1; SMN2TRPM8POLBBLM | |
| SCHEMBL20484557 | 0.72 | HTT (0.49) | KDM4ENPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024328-A1 | 2-AMINO-HETEROCYCLES AND THERAPEUTIC USES THEREFOR | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-10 | — | — | WO | disclosed |