Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896638 | 1.00 | CTSK (0.45) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL8383542 | 0.90 | CTSK (0.47) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL8383534 | 0.90 | CTSK (0.47) | CTSKCTSSMAPTGABRB1GABRB2 | |
| SCHEMBL1883313 | 0.82 | CTSK (0.50) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL12069801 | 0.81 | KLK5 (0.51) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL8895040 | 0.81 | KLK5 (0.51) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL8231291 | 0.81 | KLK5 (0.51) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL13163801 | 0.80 | GABRB1 (0.48) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL16295895 | 0.80 | CTSK (0.48) | CTSKCTSSKLK5MAPTKMT2A | |
| SCHEMBL8895205 | 0.80 | GABRB1 (0.48) | CTSKCTSSKLK5MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |