Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516857 | 0.74 | POLB (0.42) | KMT2ACYP2C19TSHRSMN1; SMN2ACE | |
| SCHEMBL9913669 | 0.71 | ABCG2 (0.72) | ALDH1A1ABCB1ABCG2 | |
| SCHEMBL9220425 | 0.70 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1HPGDACHETSHR | |
| SCHEMBL16303966 | 0.70 | ACE (0.50) | ALDH1A1KMT2AHPGDABCB1ABCG2 | |
| SCHEMBL7067688 | 0.69 | CA2 (0.54) | L3MBTL1ALDH1A1HPGDACHESMN1; SMN2 | |
| SCHEMBL5701961 | 0.69 | CA2 (0.54) | L3MBTL1ALDH1A1HPGDACHESMN1; SMN2 | |
| SCHEMBL5701920 | 0.69 | CA2 (0.54) | L3MBTL1ALDH1A1HPGDACHESMN1; SMN2 | |
| SCHEMBL7879782 | 0.68 | CA2 (0.52) | L3MBTL1ALDH1A1HPGDACHESMN1; SMN2 | |
| SCHEMBL9295024 | 0.68 | ACHE (0.45) | L3MBTL1ALDH1A1ACHETSHRRECQL | |
| Water SCHEMBL7879777 | 0.67 | CA2 (0.51) | L3MBTL1ALDH1A1HPGDACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591758-A | ANGINA PECTORIS TREATMENT | LABORATOIRES HOECHST, SA (FR) | 1997-01-07 | — | — | US | disclosed |
| EP-0604459-A1 | Organic nitrates, methods for preparing same and use thereof for treating cardiovascular diseases | LABORATOIRES HOECHST S.A. (FR) | 1994-07-06 | — | — | EP | disclosed |
| EP-0530887-A1 | Organic nitrates, processes for their preparation and their use in the treatment of cardiovascular diseases | LABORATOIRES HOECHST S.A. (FR) | 1993-03-10 | — | — | EP | disclosed |
| WO-1993003037-A1 | ORGANIC NITRATES, METHODS FOR PREPARING SAME AND USE THEREOF FOR TREATING CARDIOVASCULAR DISEASES | LABORATOIRES HOECHST, SOCIÉTÉ ANONYME (FR) | 1993-02-18 | — | — | WO | disclosed |