Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893755 | 1.00 | SLC22A6 (0.42) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL4020060 | 0.79 | — | — | |
| SCHEMBL3063573 | 0.79 | — | — | |
| SCHEMBL1405790 | 0.79 | — | — | |
| SCHEMBL4669398 | 0.78 | SLC22A6 (0.43) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL1135942 | 0.78 | SLC22A6 (0.43) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL11762118 | 0.76 | LDHA (0.47) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL2227119 | 0.76 | SLC22A6 (0.42) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL1136022 | 0.76 | SLC22A6 (0.42) | SLC22A6LDHASRRGABRR1LMNA | |
| SCHEMBL3439292 | 0.76 | SLC22A6 (0.42) | SLC22A6LDHASRRGABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594153-A | REACTING 6-HALO-3,5-DIHYDROXYHEXANOIC ACID OR DERIVATIVE THEREOF WITH DIETHER, KETONE OR UNSATURATED ETHER TO FORM 1,3-DIOXANE DERIVATIVE | E. R. SQUIBB & SONS, INC. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5457227-A | Condensing halo-substituted hydroxy ester with acetic acid, acetate salt or ester in presence of condensation agent to produce halo-substituted hydroxy keto ester | E. R. SQUIBB & SONS, INC. (US) | 1995-10-10 | — | — | US | disclosed |
| US-5278313-A | Chemical condensation reaction | E. R. SQUIBB & SONS, INC. (US) | 1994-01-11 | — | — | US | disclosed |