Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893199 | 0.79 | MAPT (0.40) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL8893417 | 0.79 | KMT2A (0.49) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL8893422 | 0.79 | KMT2A (0.49) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL3804957 | 0.79 | MAPT (0.49) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL8715367 | 0.77 | FFAR1 (0.51) | MAPTFFAR1PPARGCA2PPARA | |
| SCHEMBL6977206 | 0.77 | PPARG (0.46) | MEN1MAPTKMT2ATDP1FFAR1 | |
| SCHEMBL6968604 | 0.76 | PPARG (0.46) | MEN1MAPTKMT2ATDP1FFAR1 | |
| SCHEMBL10641731 | 0.76 | PPARG (0.49) | MEN1MAPTKMT2ATDP1FFAR1 | |
| SCHEMBL9631327 | 0.75 | MEN1 (0.54) | MEN1MAPTKMT2ATDP1FFAR1 | |
| SCHEMBL6963536 | 0.75 | PPARG (0.46) | MEN1MAPTKMT2ATDP1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043284-A1 | NEW THIAZOLIDINEDIONES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |