Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | WNT3A | P56704 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000245 | 0.89 | ALDH1A1 (0.62) | CTNNB1WNT3AHPGDPKMMAPT | |
| SCHEMBL30539184 | 0.89 | ALDH1A1 (0.62) | CTNNB1WNT3AHPGDPKMMAPT | |
| SCHEMBL26054610 | 0.82 | TSHR (0.61) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL4824992 | 0.79 | NPSR1 (0.74) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL619634 | 0.77 | MAPK1 (0.78) | TSHRCTNNB1KDM4EATMHPGD | |
| SCHEMBL26054479 | 0.76 | NPC1 (0.54) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL624490 | 0.76 | TSHR (1.00) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL29410881 | 0.76 | TSHR (1.00) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL102971 | 0.76 | KDM4E (0.89) | TSHRCTNNB1KDM4EATMWNT3A | |
| SCHEMBL828491 | 0.76 | TSHR (0.67) | TSHRCTNNB1KDM4EATMWNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5606095-A | 2-aminooxymethylenephenylacetic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| EP-0600835-B1 | Method for the production of derivatives of phenylacetic acid esters | CIBA GEIGY AG (CH) | 1996-09-11 | — | — | EP | disclosed |
| EP-0600835-A1 | Method for the production of derivatives of phenylacetic acid esters | CIBA-GEIGY AG (CH) | 1994-06-08 | — | — | EP | disclosed |