Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCKDK | O14874 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086888 | 0.83 | TMEM97 (0.46) | PPARATMEM97SIGMAR1NPY5RCNR2 | |
| SCHEMBL8893125 | 0.83 | TSHR (0.51) | TMEM97SIGMAR1ALDH1A1TSHR | |
| SCHEMBL10664881 | 0.79 | SLC6A2 (0.50) | SIGMAR1ALDH1A1RXFP1SMN1; SMN2TSHR | |
| SCHEMBL11739921 | 0.76 | LMNA (0.45) | TMEM97SIGMAR1NPY5RALDH1A1SMN1; SMN2 | |
| SCHEMBL14807739 | 0.75 | THRB (0.46) | PTGDR2PPARAALDH1A1RXFP1SMN1; SMN2 | |
| SCHEMBL14807736 | 0.75 | THRB (0.46) | PTGDR2PPARAALDH1A1RXFP1SMN1; SMN2 | |
| SCHEMBL14808375 | 0.75 | KARS1 (0.46) | PTGDR2ALDH1A1RXFP1SMN1; SMN2CNR2 | |
| SCHEMBL14808373 | 0.75 | KARS1 (0.46) | PTGDR2ALDH1A1RXFP1SMN1; SMN2CNR2 | |
| SCHEMBL10980672 | 0.73 | TMEM97 (0.45) | TMEM97SIGMAR1NPY5RALDH1A1 | |
| SCHEMBL4199934 | 0.72 | TMEM97 (0.52) | TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043282-A2 | BENZOTHIAZOLINONES AS ANTI-ASTHMATIC AGENTS | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |
| US-4049419-A | SOYBEAN PLANTS | MONSANTO COMPANY (US) | 1977-09-20 | — | — | US | disclosed |