Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.39 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572008 | 0.80 | AKR1B1 (0.43) | ALDH1A1HPGDHSD17B10HTTATM | |
| SCHEMBL3276086 | 0.74 | L3MBTL1 (0.61) | ALDH1A1HPGDHSD17B10HTTATM | |
| SCHEMBL30365583 | 0.73 | FOLH1 (0.76) | FOLH1ALDH1A1HIF1ASLC16A3KDM4E | |
| SCHEMBL70392 | 0.73 | FOLH1 (0.76) | FOLH1ALDH1A1HIF1ASLC16A3KDM4E | |
| SCHEMBL2092803 | 0.72 | L3MBTL1 (0.43) | ALDH1A1HPGDHSD17B10HTTATM | |
| SCHEMBL7183167 | 0.71 | TSHR (0.46) | PTPN1ALDH1A1LMNACYP2C9HPGD | |
| SCHEMBL9133870 | 0.70 | CYP2C9 (0.57) | FOLH1ALDH1A1CYP2C9HIF1AKDM4E | |
| SCHEMBL4243105 | 0.70 | ALDH1A1 (0.57) | FOLH1ALDH1A1LMNACYP2C9HIF1A | |
| Ethylene SCHEMBL18893737 | 0.70 | FOLH1 (0.70) | FOLH1ALDH1A1HIF1ASLC16A3KDM4E | |
| SCHEMBL8245934 | 0.70 | FOLH1 (0.59) | FOLH1ALDH1A1LMNACYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643872-A | ANTIAGGLOMERANTS FOR PLATELETS, ANTICOAGULANTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0425212-A2 | Cyclic anti-aggregatory peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |