Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.94 |
| ▸ | HTT | P42858 | 2/20 | 0.94 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.79 |
| ▸ | RAD52 | P43351 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL366842 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL5547871 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL5088590 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL668957 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL1318093 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL9179827 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397860 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397869 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL21986903 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL9172996 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111418587-A | Efficient household fabric disinfectant and preparation method thereof | 浙江施维康生物医学材料有限公司 | 2020-07-17 | — | — | CN | claimed |
| US-20130203969-A1 | USE OF SMALL MOLECULES IN METHODS FOR PURIFICATION OF BIOMOLECULES | EMD MILLIPORE CORPORATION (US) | 2013-08-08 | — | — | US | claimed |
| CN-115702122-A | Use of chloramines and cationic polymers in water treatment | 巴克曼实验室国际公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-115124428-A | Composite bactericide containing dialkyl methyl benzyl quaternary ammonium salt and preparation method thereof | 山东鑫泰水处理技术股份有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-107383161-B | Purification of biomolecules | EMD密理博公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-106574252-B | Method for purifying poliovirus from cell culture | 扬森疫苗与预防公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-111418587-A | Efficient household fabric disinfectant and preparation method thereof | 浙江施维康生物医学材料有限公司 | 2020-07-17 | — | — | CN | disclosed |
| US-10428194-B2 | Modified acrylic resin cured product, and laminate thereof, and production methods therefor | MITSUI CHEMICALS, INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3263635-B1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| US-20180163056-A1 | HYDROPHILIC CURABLE COMPOSITIONS | MITSUI CHEMICALS, INC. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-20180036995-A1 | HYDROPHILIC MONOLAYER FILM WITH OPTICAL FUNCTIONALITY AND STACK OF THE SAME | MITSUI CHEMICALS, INC. (JP) | 2018-02-08 | — | — | US | disclosed |
| US-20180030230-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS, INC. (JP) | 2018-02-01 | — | — | US | disclosed |
| EP-3270192-A1 | HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF | Mitsui Chemicals, Inc. (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-3263635-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | Mitsui Chemicals, Inc. (JP) | 2018-01-03 | — | — | EP | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-20130203969-A1 | USE OF SMALL MOLECULES IN METHODS FOR PURIFICATION OF BIOMOLECULES | EMD MILLIPORE CORPORATION (US) | 2013-08-08 | — | — | US | disclosed |
| US-5599990-A | REACTING A HALOALKANE WITH A TERT-AMINE IN THE ABSENCE OF A SOLVENT AND A STOICHIOMETRY OF NOT HIGHER THAN 1.1/1; HEATING AND STIRRING | ALBEMARLE CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |