Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.94 |
| ▸ | HTT | P42858 | 2/20 | 0.94 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.79 |
| ▸ | RAD52 | P43351 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8894051 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL366842 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL5547871 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL5088590 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL668957 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL9179827 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397860 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL22397869 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL21986903 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A | |
| Bromide SCHEMBL9172996 | 1.00 | DNM1 (0.94) | DNM1HTTHSP90AA1RAD52KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240295558-A1 | Metal Nanoparticles And Method Of Making Same | Sona Nanotech Inc. (CA) | 2024-09-05 | — | — | US | claimed |
| US-20200390908-A1 | Metal Nanoparticles and Methods of Making Same | Sona Nanotech Inc. (CA) | 2020-12-17 | — | — | US | claimed |
| US-12117447-B2 | Metal nanoparticles and methods of making same | Sona Nanotech Inc. (CA) | 2024-10-15 | — | — | US | disclosed |
| US-20240295558-A1 | Metal Nanoparticles And Method Of Making Same | Sona Nanotech Inc. (CA) | 2024-09-05 | — | — | US | disclosed |
| US-20200390908-A1 | Metal Nanoparticles and Methods of Making Same | Sona Nanotech Inc. (CA) | 2020-12-17 | — | — | US | disclosed |
| EP-3703886-A1 | METAL NANOPARTICLES AND METHODS OF MAKING SAME | Sona Nanotech (CA) | 2020-09-09 | — | — | EP | disclosed |
| CN-111185307-A | Application of gemini quaternary ammonium salt collecting agent | 南昌航空大学 | 2020-05-22 | — | — | CN | disclosed |
| CN-111185307-A | Application of gemini quaternary ammonium salt collecting agent | 南昌航空大学 | 2020-05-22 | — | — | CN | disclosed |
| US-20110269652-A1 | GEMINI SURFACTANTS | ST. FRANCIS XAVIER UNIVERSITY (CA) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240295558-A1 | Metal Nanoparticles And Method Of Making Same | SOD1, SLC39A3, SLC30A7 | DNM1 219/4885HTT 2302/4885HSP90AA1 3583/4885 |
| US-20200390908-A1 | Metal Nanoparticles and Methods of Making Same | SOD1, SLC39A3, SLC30A7 | DNM1 318/4885HTT 2242/4885HSP90AA1 3393/4885 |
| US-20110269652-A1 | GEMINI SURFACTANTS | SGMS1, DEGS1, GMNN | DNM1 2074/4885HTT 1291/4885HSP90AA1 3009/4885 |
| US-12117447-B2 | Metal nanoparticles and methods of making same | SOD1, SLC39A3, SLC30A7 | DNM1 318/4885HTT 2242/4885HSP90AA1 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.