SCHEMBL8894501

SCHEMBL8894501

O=CC(CO)N1CCCC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.35
FDPS P14324 2/20 0.33
MAPT P10636 1/20 0.33
ATM Q13315 1/20 0.33
HSD17B10 Q99714 1/20 0.31
DPP7 Q9UHL4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5917521 0.76
SCHEMBL8904323 0.76 SLC6A2 (0.30)
SCHEMBL19415030 0.74 DPP7 (0.34) FDPSMAPTHSD17B10DPP7
SCHEMBL12522742 0.74 MAPT (0.32) FDPSMAPTHSD17B10DPP7
SCHEMBL9329803 0.74 FDPS (0.32) FDPSMAPTATMDPP7
SCHEMBL10895288 0.73 HSD17B10 (0.41) MAPTATMHSD17B10
SCHEMBL455166 0.73 SLC6A2 (0.40)
SCHEMBL5182689 0.73 SLC6A3 (0.38)
SCHEMBL10900189 0.73
SCHEMBL454027 0.73 SLC6A2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5620959-A OLIGOPEPTIDES OR POLYPEPTIDES AS ANTISECRETORY AGENTS, ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS GLAXO WELLCOME INC. (US) 1997-04-15 US claimed
EP-0541654-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1993-05-19 EP claimed
WO-1992002545-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1992-02-20 WO claimed
US-5620959-A OLIGOPEPTIDES OR POLYPEPTIDES AS ANTISECRETORY AGENTS, ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS GLAXO WELLCOME INC. (US) 1997-04-15 US disclosed
EP-0541654-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1993-05-19 EP disclosed
EP-0541654-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1993-05-19 EP disclosed
WO-1992002545-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1992-02-20 WO disclosed
WO-1992002545-A1 BOMBESIN ANTAGONISTS THE WELLCOME FOUNDATION LIMITED (GB) 1992-02-20 WO disclosed