SCHEMBL8904323

SCHEMBL8904323

CCC(C=O)N1CCCC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12522742 0.98 MAPT (0.32)
SCHEMBL5182689 0.82 SLC6A3 (0.38) SLC6A2SLC6A4SLC6A3
SCHEMBL23668191 0.82 HTR1A (0.31) SLC6A3
SCHEMBL15515534 0.80 ALDH1A1 (0.40)
SCHEMBL27711019 0.80 SLC6A3 (0.37) SLC6A2SLC6A4SLC6A3
SCHEMBL8902843 0.80 SLC6A2 (0.35) SLC6A2SLC6A4
SCHEMBL455166 0.77 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL452571 0.77 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL454027 0.77 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3
SCHEMBL8904040 0.77 TSHR (0.41) SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110320295-A A kind of detection method of 1- phenyl -2- (N- pyrrolidinyl) -1- butanone 公安部物证鉴定中心 2019-10-11 CN claimed
US-5610315-A Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1997-03-11 US disclosed
US-5484954-A HEATING, DEACYLATING NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-01-16 US disclosed
US-5302730-A Acylation with acetic acid at positions one and seven; eliminating acyl group at position seven by solvolysis NIPPON KAYAKU KK (JP) 1994-04-12 US disclosed
EP-0297496-B1 Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KK (JP) 1994-01-19 EP disclosed
CN-1016869-B Process for preparing 6, 7-diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KK (JP) 1992-06-03 CN disclosed
CN-1030583-A Preparation 6,7-diacyl-7-takes off the novel method of acetyl forskrine derivant NIPPON KAYAKU KK (JP) 1989-01-25 CN disclosed
EP-0297496-A2 Novel process for the preparation of 6,7-Diacyl-7-deacetylforskolin derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-01-04 EP disclosed