Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731967 | 0.85 | ALDH1A1 (0.32) | NPC1L3MBTL1ALDH1A1KDM4ERAB9A | |
| SCHEMBL28211033 | 0.78 | GABRG2 (0.47) | NOTUMIDO1NPC1MPLL3MBTL1 | |
| SCHEMBL34461976 | 0.78 | GABRG2 (0.47) | NOTUMIDO1NPC1MPLL3MBTL1 | |
| SCHEMBL29516219 | 0.76 | NISCH (0.38) | NPC1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22344712 | 0.76 | LMNA (0.47) | IDO1NPC1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7913045 | 0.76 | NPC1 (0.44) | IDO1NPC1L3MBTL1CASP3SENP8 | |
| SCHEMBL45025 | 0.76 | IDO1 (0.43) | IDO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL29501476 | 0.76 | IDO1 (0.43) | IDO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL6017122 | 0.76 | ALDH1A1 (0.52) | IDO1NPC1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL30332425 | 0.76 | NISCH (0.38) | NPC1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020827-A1 | FLUOROPHENYL-TRIAZINE AND PYRIMIDINE DERIVATIVES AS COMPOUNDS ACTING ON THE CENTRAL NERVOUS SYSTEM | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1997-06-12 | — | — | WO | claimed |
| WO-1997020827-A1 | FLUOROPHENYL-TRIAZINE AND PYRIMIDINE DERIVATIVES AS COMPOUNDS ACTING ON THE CENTRAL NERVOUS SYSTEM | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 1997-06-12 | — | — | WO | disclosed |