Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 12/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.53 |
| ▸ | PPARA | Q07869 | 10/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893413 | 0.95 | PPARD (0.52) | PPARDPPARGPPARAESR1 | |
| SCHEMBL8699477 | 0.86 | PPARD (0.54) | PPARDPPARGPPARA | |
| SCHEMBL6527568 | 0.74 | PPARD (0.75) | PPARDPPARGPPARAESR1FFAR1 | |
| Oxalic Acid SCHEMBL28079977 | 0.73 | MAOA (0.68) | — | |
| SCHEMBL6474346 | 0.72 | PPARD (0.92) | PPARDPPARGPPARA | |
| SCHEMBL6474345 | 0.72 | PPARD (0.92) | PPARDPPARGPPARA | |
| SCHEMBL6474343 | 0.72 | PPARD (0.92) | PPARDPPARGPPARA | |
| SCHEMBL12442803 | 0.71 | PPARD (0.55) | PPARDPPARGPPARA | |
| Oxalic Acid SCHEMBL31633759 | 0.71 | TAAR1 (0.61) | — | |
| SCHEMBL11332779 | 0.71 | ALOX15 (0.53) | PPARDPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997048674-A1 | DIARYL ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-24 | — | — | WO | disclosed |