Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212433 | 0.85 | MAPT (0.50) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8894146 | 0.82 | MAPT (0.44) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5950512 | 0.81 | KDM4E (0.52) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL15577833 | 0.81 | LMNA (0.51) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL988048 | 0.81 | THRB (0.57) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1066414 | 0.80 | KDM4E (0.51) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL11674113 | 0.80 | NPSR1 (0.67) | ALDH1A1NPSR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11674769 | 0.80 | ALDH1A1 (0.45) | MAPTALDH1A1NPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12088129 | 0.80 | TDP1 (0.61) | MAPTALDH1A1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL16039243 | 0.80 | HCAR2 (0.51) | MAPTALDH1A1NPSR1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |