Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895198 | 0.87 | AKT1 (0.39) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL18522814 | 0.83 | LMNA (0.51) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL5564818 | 0.83 | LMNA (0.51) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL7781713 | 0.83 | LMNA (0.51) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL5564821 | 0.83 | LMNA (0.51) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL3050394 | 0.82 | MEN1 (0.49) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL8894809 | 0.81 | MEN1 (0.35) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL8895723 | 0.80 | MEN1 (0.34) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL8713431 | 0.77 | MMP1 (0.44) | RIPK1MEN1KMT2AADRA2BADRA2C | |
| SCHEMBL22957214 | 0.77 | MEN1 (0.47) | MEN1KMT2AADRA2BADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |