Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3050394 | 0.83 | MEN1 (0.49) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL3039559 | 0.81 | NR4A2 (0.55) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL7372235 | 0.81 | NR4A2 (0.55) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8710897 | 0.80 | MMP1 (0.36) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL25962753 | 0.80 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL3046435 | 0.80 | NR4A2 (0.54) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL9068483 | 0.80 | ADRA2B (0.41) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL9068424 | 0.79 | MMP1 (0.39) | MMP1MMP3MMP2MMP9MMP8 | |
| SCHEMBL8894571 | 0.77 | RIPK1 (0.43) | ADRA2BADRA2CSLC6A2HTR2ASLC6A4 | |
| SCHEMBL28784089 | 0.76 | MMP1 (0.50) | MMP1MMP3MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5821222-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5529984-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |