Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.57 |
| ▸ | CCKBR | P32239 | 3/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 3/20 | 0.52 |
| ▸ | NPY2R | P49146 | 3/20 | 0.52 |
| ▸ | NPY4R | P50391 | 3/20 | 0.52 |
| ▸ | GHSR | Q92847 | 3/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894394 | 0.96 | CCKBR (0.59) | CTSCCCKBRCCKARNPY1RNPY2R | |
| SCHEMBL8892946 | 0.93 | CTSC (0.55) | CTSCCCKBRCCKARECE1NPY1R | |
| SCHEMBL8893123 | 0.92 | CCKBR (0.56) | CTSCCCKBRCCKARNPY1RNPY2R | |
| SCHEMBL8896053 | 0.91 | ECE1 (0.60) | ECE1MEN1KMT2AGHSRACE | |
| SCHEMBL8894262 | 0.91 | ECE1 (0.60) | ECE1MEN1KMT2AGHSRACE | |
| SCHEMBL30052009 | 0.90 | CTSC (0.64) | CTSCCCKBRCCKARECE1MEN1 | |
| SCHEMBL30051511 | 0.90 | CTSC (0.64) | CTSCECE1MEN1KMT2AACE | |
| SCHEMBL8894358 | 0.90 | CCKBR (0.59) | CTSCCCKBRCCKARECE1GHSR | |
| SCHEMBL30051770 | 0.89 | CTSC (0.65) | CTSCCCKBRCCKARECE1MEN1 | |
| SCHEMBL29356416 | 0.89 | CTSC (0.67) | CTSCCCKBRCCKARECE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | claimed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | claimed |
| US-5661128-A | TREATING CANCER | MERCK & CO. INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996010037-A1 | PEPTIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |