Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 2/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027978 | 1.00 | NAT1 (0.56) | NAT1HSD17B3CISD1MAOBMAOA | |
| SCHEMBL8896050 | 0.80 | TNKS2 (0.38) | NAT1MEN1KMT2A | |
| SCHEMBL8893765 | 0.75 | TNKS2 (0.36) | — | |
| SCHEMBL9684884 | 0.74 | TNKS2 (0.39) | NAT1CISD1MAOBMAOAMEN1 | |
| SCHEMBL9684891 | 0.74 | TNKS2 (0.39) | NAT1CISD1MAOBMAOAMEN1 | |
| SCHEMBL8536492 | 0.72 | NAT1 (0.69) | NAT1HSD17B3CISD1MAOBMAOA | |
| SCHEMBL8933387 | 0.72 | HSD17B3 (0.49) | NAT1HSD17B3CISD1MAOAMEN1 | |
| SCHEMBL8893373 | 0.72 | HSD17B3 (0.49) | NAT1HSD17B3CISD1MAOAMEN1 | |
| SCHEMBL8198993 | 0.69 | NAT1 (0.69) | NAT1HSD17B3CISD1MAOBMAOA | |
| SCHEMBL7246589 | 0.69 | NAT1 (0.69) | NAT1HSD17B3CISD1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691367-A | ANTIINFLAMMATORY AGENTS OR ANTIARTHRITIC AGENTS | ELI LILLY AND COMPANY (US) | 1997-11-25 | — | — | US | disclosed |
| EP-0391644-B1 | Aryl-substituted rhodanine derivatives | LILLY CO ELI (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5356917-A | Antiischemic, antiinflammatory, antiarthritic agents, treat-ment of dystrophic mammals | ELI LILLY AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |
| US-5158966-A | Aryl-substituted rhodanine derivatives | THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0391644-A2 | Aryl-substituted rhodanine derivatives | ELI LILLY AND COMPANY (US) | 1990-10-10 | — | — | EP | disclosed |