Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 3/20 | 0.34 |
| ▸ | NAT1 | P18440 | 2/20 | 0.33 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684891 | 1.00 | TNKS2 (0.39) | TNKS2IGF1RNAT1CISD1PTPN1 | |
| SCHEMBL8534279 | 0.81 | CYP1A2 (0.41) | IGF1RNAT1CISD1CYP1A2CYP3A4 | |
| SCHEMBL8896050 | 0.79 | TNKS2 (0.38) | TNKS2NAT1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8893765 | 0.77 | TNKS2 (0.36) | TNKS2CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL8894717 | 0.74 | NAT1 (0.56) | NAT1CISD1MEN1MAPTKMT2A | |
| SCHEMBL9027978 | 0.74 | NAT1 (0.56) | NAT1CISD1MEN1MAPTKMT2A | |
| SCHEMBL8535042 | 0.73 | MEN1 (0.43) | IGF1RNAT1CISD1PTPN1CDC25B | |
| SCHEMBL3263476 | 0.68 | PTGS2 (0.64) | CYP1A2CYP2C9GAAPTGS2PTGS1 | |
| SCHEMBL28499090 | 0.65 | TNKS2 (0.46) | TNKS2CYP3A4ALDH1A1MAOA | |
| SCHEMBL8536501 | 0.65 | PTGS2 (0.55) | CYP1A2CYP2C9MEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500337-A1 | Composition containing aryl-substituted rhodanine derivatives for the treatment of type I diabetes | UNIVERSITY OF COLORADO FOUNDATION, INC. (US) | 1992-08-26 | — | — | EP | disclosed |