SCHEMBL889472

SCHEMBL889472

CC[Si](CC)(CC)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10516315 0.79
SCHEMBL8056116 0.75
SCHEMBL8056118 0.75
SCHEMBL3873047 0.69
SCHEMBL32690762 0.69 ALDH1A1 (0.33)
SCHEMBL5925246 0.69
SCHEMBL9775422 0.69 TSHR (0.33) TSHR
SCHEMBL20328584 0.69
SCHEMBL7147605 0.67
SCHEMBL8896173 0.67 TSHR (0.33) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 US disclosed
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230276697-A1 ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-08-31 US disclosed
US-11690285-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed
US-20230125206-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20180179120-A1 Atropisomers and Methods of Altering Enantiomeric Excess FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. 2018-06-28 US disclosed
US-20120010281-A1 ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125206-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, ODC1, OCIAD2 TSHR 3103/4885TDP1 3738/4885
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND TSHR 4120/4885TDP1 186/4885
US-20230276697-A1 ELECTROLUMINESCENT DEVICES ELAVL1, ELAVL3, JUND TSHR 4120/4885TDP1 186/4885
US-20230337523-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OCIAD1, OCIAD2 TSHR 296/4885TDP1 3866/4885
US-11690285-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND TSHR 4120/4885TDP1 186/4885
US-20120010281-A1 ANTIMICROBIAL AND ANTITUBERCULAR COMPOUNDS TBK1, TBCD, TBKBP1 TSHR 1584/4885TDP1 3356/4885
US-20180179120-A1 Atropisomers and Methods of Altering Enantiomeric Excess CYP11B2, CYP21A2, CYP11B1 TSHR 2049/4885TDP1 527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.