Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 7/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753810 | 0.85 | AKT1 (0.39) | LMNAPOLBPKMMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9753577 | 0.84 | AKT1 (0.39) | LMNAPOLBPKMMAPTKMT2A | |
| SCHEMBL8894816 | 0.84 | FKBP1A (0.39) | FKBP1AKMT2AMEN1EPHX1ALDH1A1 | |
| SCHEMBL8568541 | 0.76 | MME (0.31) | — | |
| SCHEMBL28195125 | 0.74 | MAPK1 (0.31) | — | |
| Isopropylamine SCHEMBL8572293 | 0.72 | MME (0.31) | — | |
| SCHEMBL28891519 | 0.71 | EPHX1 (0.31) | EPHX1 | |
| SCHEMBL5330628 | 0.68 | KMT2A (0.49) | KMT2AL3MBTL1 | |
| SCHEMBL30645025 | 0.66 | MFN2 (0.51) | POLBFKBP1ASIGMAR1KMT2AALDH1A1 | |
| SCHEMBL27028429 | 0.66 | MFN2 (0.51) | POLBFKBP1ASIGMAR1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |