Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894794 | 0.84 | LMNA (0.40) | FKBP1AMEN1KMT2AEPHX1ALDH1A1 | |
| SCHEMBL9753810 | 0.73 | AKT1 (0.39) | MEN1KMT2ACHRM3ALDH1A1PDE4A | |
| SCHEMBL8568541 | 0.72 | MME (0.31) | — | |
| Hydrochloric Acid SCHEMBL9753577 | 0.72 | AKT1 (0.39) | MEN1KMT2ACHRM3ALDH1A1PDE4A | |
| SCHEMBL8103699 | 0.70 | STAT3 (0.41) | FKBP1AMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL28195125 | 0.68 | MAPK1 (0.31) | — | |
| Isopropylamine SCHEMBL8572293 | 0.68 | MME (0.31) | — | |
| Bicarbonate SCHEMBL8103701 | 0.67 | KMT2A (0.47) | FKBP1AMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8894806 | 0.66 | KMT2A (0.43) | FKBP1AMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8241380 | 0.66 | CA12 (0.53) | MTNR1AMTNR1BPLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677297-A | ENZYME INHIBITOR FOR TREATING THE HEART FAILURE TO REDUCE THE CARDIAC PRESSURE, DIURETICS | SOLVAY PHARMACEUTICALS GMBH (DE) | 1997-10-14 | — | — | US | disclosed |