SCHEMBL6547658

SCHEMBL6547658

O=C(c1ccccc1)c1ccc(OCCCOc2c(Cl)cc(OCC=C(Cl)Cl)cc2Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.48
GAA P10253 1/20 0.48
LMNA P02545 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
MAPT P10636 2/20 0.46
PPARG P37231 5/20 0.45
PPARD Q03181 3/20 0.45
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 3/20 0.42
HRH4 Q9H3N8 1/20 0.42
LTA4H P09960 1/20 0.42
LSS P48449 2/20 0.42
ALDH1A1 P00352 2/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8022439 0.98 PPARA (0.51) PPARAGAALMNAL3MBTL1MAPT
SCHEMBL8894826 0.90 PLA2G4B (0.46) L3MBTL1MAPK1ALDH1A1HTT
SCHEMBL8408702 0.88 KCNA3 (0.41) L3MBTL1MAPTMAPK1ALDH1A1HTT
SCHEMBL7616746 0.87 PPARA (0.38) PPARAGAALMNAL3MBTL1MAPT
SCHEMBL8894549 0.87 TP53 (0.47) L3MBTL1ALDH1A1HTT
SCHEMBL6548606 0.87 MAPT (0.43) PPARAGAALMNAL3MBTL1MAPT
SCHEMBL8897462 0.86 TP53 (0.49) L3MBTL1ALDH1A1HTT
SCHEMBL6547877 0.86 L3MBTL1 (0.51) GAALMNAL3MBTL1MAPTKDM4E
SCHEMBL15382888 0.86 LTA4H (0.43) PPARAPPARGPPARDLTA4HHTT
SCHEMBL7615610 0.85 LSS (0.39) PPARAGAALMNAL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP claimed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO claimed
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed
EP-0975586-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION Sumitomo Chemical Company, Limited (JP) 2000-02-02 EP disclosed
WO-1998045254-A2 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 PPARA 2987/4885GAA 3855/4885LMNA 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.