Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22481057 | 0.79 | LMNA (0.53) | CA1CA2CA9CA5ASLC6A3 | |
| SCHEMBL28680548 | 0.76 | ALDH1A1 (0.53) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL649457 | 0.76 | CA1 (0.71) | CA1CA2CA9CA5AKMT2A | |
| Hydrochloric Acid SCHEMBL18050033 | 0.76 | PARP1 (0.41) | CA1CA2CA9CA5ASLC6A3 | |
| SCHEMBL27931493 | 0.74 | CA1 (0.50) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL16950353 | 0.73 | LMNA (0.47) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL2655486 | 0.73 | LMNA (0.61) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL7870569 | 0.73 | ALDH1A1 (0.48) | KMT2ATSHRLMNAGAAKDM4E | |
| SCHEMBL26162755 | 0.73 | LMNA (0.47) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL18762939 | 0.73 | CA9 (0.38) | CA1CA2CA9CA5AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693672-A | 3,4,5-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic and medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |