Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895359 | 0.92 | HSD17B10 (0.49) | HSD17B10ALDH1A1POLBMMP9MMP13 | |
| SCHEMBL8896960 | 0.89 | ALDH1A1 (0.49) | ALDH1A1NPSR1TBXAS1ATML3MBTL1 | |
| SCHEMBL8898417 | 0.89 | ALDH1A1 (0.52) | ALDH1A1NPSR1MMP9MMP2HDAC1 | |
| SCHEMBL8418163 | 0.88 | TBXAS1 (0.49) | ALDH1A1NPSR1TBXAS1ATML3MBTL1 | |
| SCHEMBL8896796 | 0.88 | FFAR1 (0.49) | ALDH1A1NPSR1TBXAS1ATML3MBTL1 | |
| SCHEMBL8896292 | 0.88 | NPSR1 (0.48) | ALDH1A1NPSR1MMP9MMP13MMP2 | |
| SCHEMBL8417505 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBNPSR1TBXAS1MMP9 | |
| SCHEMBL8895718 | 0.87 | ALDH1A1 (0.49) | ALDH1A1POLBNPSR1TBXAS1MMP9 | |
| SCHEMBL8894873 | 0.87 | TBXAS1 (0.50) | ALDH1A1NPSR1TBXAS1ATML3MBTL1 | |
| SCHEMBL8895793 | 0.87 | TBXAS1 (0.50) | ALDH1A1NPSR1TBXAS1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |