SCHEMBL8896796

SCHEMBL8896796

CCCCCC(NS(=O)(=O)c1ccc(F)cc1)c1ccc(CCCC(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
ALDH1A1 P00352 3/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
LMNA P02545 1/20 0.46
SIGMAR1 Q99720 1/20 0.43
CYSLTR2 Q9NS75 1/20 0.42
CYSLTR1 Q9Y271 1/20 0.42
TBXAS1 P24557 1/20 0.42
METAP2 P50579 1/20 0.41
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 3/20 0.41
S1PR2 O95136 2/20 0.41
EEF2K O00418 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8898633 0.99 FFAR1 (0.48) FFAR1FFAR4NPSR1ALDH1A1ATM
SCHEMBL8895062 0.97 FFAR1 (0.50) FFAR1FFAR4NPSR1ALDH1A1ATM
SCHEMBL8897965 0.92 NPSR1 (0.51) FFAR1FFAR4NPSR1ALDH1A1ATM
SCHEMBL8896960 0.91 ALDH1A1 (0.49) NPSR1ALDH1A1ATML3MBTL1CYSLTR2
SCHEMBL8898417 0.90 ALDH1A1 (0.52) NPSR1ALDH1A1ATML3MBTL1CYSLTR2
SCHEMBL8896101 0.90 FFAR1 (0.47) FFAR1FFAR4NPSR1ALDH1A1ATM
SCHEMBL8896292 0.90 NPSR1 (0.48) NPSR1ALDH1A1ATML3MBTL1CYSLTR2
SCHEMBL8896727 0.90 NPSR1 (0.51) FFAR1FFAR4NPSR1ALDH1A1ATM
SCHEMBL8418163 0.90 TBXAS1 (0.49) NPSR1ALDH1A1ATML3MBTL1CYSLTR2
SCHEMBL8419542 0.90 LMNA (0.46) FFAR1FFAR4NPSR1ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0663392-A1 BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF HOKURIKU SEIYAKU CO., LTD. (JP) 1995-07-19 EP claimed
US-5597848-A PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS HOKURIKU SEIYAKU CO., LTD. (JP) 1997-01-28 US disclosed
EP-0663392-A1 BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF HOKURIKU SEIYAKU CO., LTD. (JP) 1995-07-19 EP disclosed