SCHEMBL889532

SCHEMBL889532

OCC1O[C@@H](OCCS)C(O)[C@@H](O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.62
LGALS3 P17931 3/20 0.62
LGALS4 P56470 3/20 0.62
GAA P10253 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.46
TYR P14679 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16129417 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18746352 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL10070674 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18746353 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18387240 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18383020 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL10298049 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL16900305 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL18387241 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1
SCHEMBL13895786 1.00 LGALS8 (0.62) LGALS8LGALS3LGALS4GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9623123-B2 Fluorescent conjugated polymers with a bodipy-based backbone and uses thereof MICHIGAN TECHNOLOGICAL UNIVERSITY (US) 2017-04-18 US disclosed
US-9474687-B2 Combination peptide-nanoparticles and delivery systems incorporating same MONOSOL RX, LLC (US) 2016-10-25 US disclosed
US-20150190476-A1 NANOPARTICLE FILM DELIVERY SYSTEMS MONOSOL RX, INC. 2015-07-09 US disclosed
US-20150099698-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION 2015-04-09 US disclosed
US-8974826-B2 Nanoparticle film delivery systems MONOSOL RX, LLC (US) 2015-03-10 US disclosed
US-8790704-B2 Combination peptide-nanoparticles and delivery systems incorporating same MONOSOL RX, LLC (US) 2014-07-29 US disclosed
US-8568781-B2 Peptide-carrying nanoparticles MIDATECH LIMITED (GB) 2013-10-29 US disclosed
US-20120301535-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME AQUESTIVE THERAPEUTICS, INC. 2012-11-29 US disclosed
US-20120171291-A1 PEPTIDE-CARRYING NANOPARTICLES MIDATECH PHARMA PLC (GB) 2012-07-05 US disclosed
US-20120009260-A1 NANOPARTICLE FILM DELIVERY SYSTEMS AQUESTIVE THERAPEUTICS, INC. 2012-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120171291-A1 PEPTIDE-CARRYING NANOPARTICLES CALCA, LNPEP, CLTA LGALS8 160/4885LGALS3 99/4885LGALS4 134/4885
US-20150099698-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME CALCA, LNPEP, IAPP LGALS8 260/4885LGALS3 156/4885LGALS4 196/4885
US-20120009260-A1 NANOPARTICLE FILM DELIVERY SYSTEMS CD63, DSTN, EPCAM LGALS8 878/4885LGALS3 369/4885LGALS4 1202/4885
US-20150190476-A1 NANOPARTICLE FILM DELIVERY SYSTEMS CD63, DSTN, EPCAM LGALS8 878/4885LGALS3 369/4885LGALS4 1202/4885
US-20120301535-A1 COMBINATION PEPTIDE-NANOPARTICLES AND DELIVERY SYSTEMS INCORPORATING SAME CALCA, LNPEP, IAPP LGALS8 260/4885LGALS3 156/4885LGALS4 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.