Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788957 | 1.00 | ACHE (0.38) | ACHESIRT2SIRT1CA12CA9 | |
| SCHEMBL12570181 | 0.94 | TK1 (0.40) | — | |
| SCHEMBL889535 | 0.94 | TK1 (0.40) | — | |
| SCHEMBL12570183 | 0.87 | TOP2A (0.41) | — | |
| SCHEMBL12762673 | 0.87 | TOP2A (0.41) | — | |
| SCHEMBL14665890 | 0.85 | P2RY2 (0.49) | — | |
| SCHEMBL26233701 | 0.82 | TK1 (0.43) | — | |
| SCHEMBL26233704 | 0.82 | CA12 (0.36) | ACHECA12CA9 | |
| SCHEMBL26233706 | 0.78 | RNASE1 (0.41) | CA12CA9 | |
| SCHEMBL2056807 | 0.75 | TK1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361727-B2 | 3′OH-unblocked, nucleotides and nucleosides base modified with labels and photocleavable, terminating groups and methods for their use in DNA sequencing | LASERGEN, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-20110287427-A1 | 3'OH-UNBLOCKED, NUCLEOTIDES AND NUCLEOSIDES BASE MODIFIED WITH LABELS AND PHOTOCLEAVABLE, TERMINATING GROUPS AND METHODS FOR THEIR USE IN DNA SEQUENCING | LASERGEN, INC. (US) | 2011-11-24 | — | — | US | disclosed |