Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | APLNR | P35414 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15514216 | 0.78 | SLC6A4 (0.55) | SLC6A4APLNRCYP2C19CYP1A2ALOX15 | |
| SCHEMBL1979427 | 0.75 | SLC6A4 (0.52) | SLC6A4APLNRCYP2C19CYP1A2ALOX15 | |
| SCHEMBL2681249 | 0.75 | — | — | |
| SCHEMBL2897770 | 0.75 | — | — | |
| SCHEMBL294740 | 0.75 | — | — | |
| SCHEMBL5501845 | 0.73 | APLNR (0.80) | SLC6A4APLNRCYP2C19CYP1A2ALOX15 | |
| SCHEMBL4755338 | 0.73 | SLC6A4 (0.59) | SLC6A4APLNRCYP2C19CYP1A2ALOX15 | |
| SCHEMBL20657000 | 0.72 | APLNR (0.41) | SLC6A4APLNRCYP2C19CYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL5121110 | 0.72 | — | — | |
| Bromide SCHEMBL10884077 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677285-A | PERACYLATION; SALT FORMATION | FIDIA S.P.A. (IT) | 1997-10-14 | — | — | US | disclosed |
| EP-0652887-A1 | NEW DERIVATIVES OF NEURAMINIC ACID | FIDIA S.p.A. (IT) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994003469-A1 | NEW DERIVATIVES OF NEURAMINIC ACID | FIDIA S.P.A. (IT) | 1994-02-17 | — | — | WO | disclosed |
| US-4383937-A | Aqueous functional fluid compositions | CINCINNATI MILACRON INC. (US) | 1983-05-17 | — | — | US | disclosed |