Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GPR183 | P32249 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895505 | 1.00 | DRD2 (0.37) | DRD2ESR1ESR2DRD3TMEM97 | |
| SCHEMBL8897546 | 0.82 | ESR1 (0.38) | DRD2ESR1ESR2DRD3 | |
| SCHEMBL8897540 | 0.82 | ESR1 (0.38) | DRD2ESR1ESR2DRD3 | |
| SCHEMBL8565938 | 0.81 | TMEM97 (0.37) | ESR1ESR2DRD3TMEM97SIGMAR1 | |
| SCHEMBL8562609 | 0.69 | ESR1 (0.44) | ESR1ESR2DRD3TMEM97SIGMAR1 | |
| SCHEMBL7423187 | 0.68 | ESR1 (0.39) | ESR1ESR2 | |
| SCHEMBL8565611 | 0.68 | DCUN1D1 (0.39) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL8565613 | 0.68 | DCUN1D1 (0.39) | ESR1ESR2MEN1KMT2A | |
| SCHEMBL8896148 | 0.67 | MCHR1 (0.41) | — | |
| SCHEMBL8896160 | 0.67 | MCHR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612335-A | ANTICOAGULANTS; COMBATING/PREVENTING DISEASES WHERE CELL AGGREGATES OCCUR OR CELL-MATRIX INTERACTIONS PLAY A PART | KARL THOMAE GMBH (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5519036-A | IMIDAZOLIDINONES, ANTICOAGULANTS, CELL AGGREGATION PREVENTION | KARL THOMAE GMBH (DE) | 1996-05-21 | — | — | US | disclosed |