Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 9/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895514 | 0.81 | DRD2 (0.37) | TMEM97SIGMAR1CHRM4DRD3HTT | |
| SCHEMBL8895505 | 0.81 | DRD2 (0.37) | TMEM97SIGMAR1CHRM4DRD3HTT | |
| SCHEMBL8558153 | 0.69 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL8562609 | 0.68 | ESR1 (0.44) | TMEM97SIGMAR1HTR1ACHRM5HRH2 | |
| SCHEMBL8558150 | 0.68 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL17968898 | 0.66 | HTT (0.57) | HTTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL8565613 | 0.64 | DCUN1D1 (0.39) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL8565611 | 0.64 | DCUN1D1 (0.39) | ESR1ESR2KDM4EMEN1KMT2A | |
| SCHEMBL9237582 | 0.64 | ENPP2 (0.50) | SIGMAR1HTTPTGDR2MEN1KMT2A | |
| SCHEMBL1640514 | 0.64 | ESR1 (0.51) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827849-A | HAVING INHIBITORY EFFECT ON INFLAMMATION AND BONE DEGRADATION, ANTITHROMBOTIC, ANTIAGGREGATORY AND TUMOR- OR METASTASIS-INHIBITING EFFECT | KARL THOMAE GMBH (DE) | 1998-10-27 | — | — | US | disclosed |