Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894761 | 0.97 | ADAMTS5 (0.53) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8896354 | 0.93 | NPSR1 (0.53) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8895575 | 0.93 | NPSR1 (0.56) | ADAMTS5MMP2TBXA2RALDH1A1NPSR1 | |
| SCHEMBL8896241 | 0.90 | ADAMTS5 (0.48) | ADAMTS5MMP2ALDH1A1TP53GAA | |
| SCHEMBL8897096 | 0.89 | TBXAS1 (0.52) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8895021 | 0.89 | NPSR1 (0.52) | MMP2TBXA2RALDH1A1NPSR1MAPT | |
| SCHEMBL8896483 | 0.88 | TBXAS1 (0.53) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8898142 | 0.88 | S1PR1 (0.49) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8895461 | 0.88 | S1PR1 (0.49) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 | |
| SCHEMBL8898502 | 0.88 | IDO1 (0.49) | ADAMTS5MMP2TBXA2RTBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |