SCHEMBL8895560

SCHEMBL8895560

CC[CH]OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.55
LMNA P02545 2/20 0.52
TSHR P16473 5/20 0.52
PAM P19021 2/20 0.50
MAPT P10636 2/20 0.48
MAPK1 P28482 1/20 0.48
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
PPARG P37231 6/20 0.46
PPARD Q03181 6/20 0.46
PPARA Q07869 6/20 0.46
HDAC11 Q96DB2 5/20 0.46
GPR84 Q9NQS5 4/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
PTPN1 P18031 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894360 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL938866 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8895726 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8849361 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8812077 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8893734 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8894556 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8896962 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8894824 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT
SCHEMBL8893917 1.00 DGKA (0.55) DGKALMNATSHRPAMMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025928-A1 CARDIOPROTECTIVE LIPIDS AND METHODS OF USE SIGNPATH PHARMA INC (US) 2024-01-25 US disclosed
US-11746119-B2 Cardiopathy-reducing phosphodiester lipids SIGNPATH PHARMA, INC. (US) 2023-09-05 US disclosed
US-11643424-B2 Cardiopathy-reducing phosphodiester lipids SIGNPATH PHARMA, INC. (US) 2023-05-09 US disclosed
US-20220056057-A1 Novel Lipids SIGNPATH PHARMA INC. 2022-02-24 US disclosed
US-20210198294-A1 Novel Lipids SIGNPATH PHARMA INC. 2021-07-01 US disclosed
EP-3813820-A1 NOVEL LIPIDS Signpath Pharma, Inc. (US) 2021-05-05 EP disclosed
US-10975111-B2 Cardiopathy-reducing phosphodiester lipids SIGNPATH PHARMA, INC. (US) 2021-04-13 US disclosed
US-5670563-A ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND CIBA-SPECIALTY CHEMICALS CORPORATION (US) 1997-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220056057-A1 Novel Lipids LCAT, LIPC, CETP DGKA 195/4885LMNA 1179/4885TSHR 4029/4885
US-11746119-B2 Cardiopathy-reducing phosphodiester lipids TNNT2, TNNI3, FABP3 DGKA 70/4885LMNA 385/4885TSHR 3890/4885
US-20240025928-A1 CARDIOPROTECTIVE LIPIDS AND METHODS OF USE CPT1B, FABP3, NR1H2 DGKA 897/4885LMNA 262/4885TSHR 1085/4885
US-20210198294-A1 Novel Lipids LCAT, LIPC, CETP DGKA 195/4885LMNA 1182/4885TSHR 4029/4885
US-11643424-B2 Cardiopathy-reducing phosphodiester lipids TNNT2, TNNI3, FABP3 DGKA 70/4885LMNA 385/4885TSHR 3890/4885
US-10975111-B2 Cardiopathy-reducing phosphodiester lipids TNNT2, TNNI3, FABP3 DGKA 70/4885LMNA 385/4885TSHR 3890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.