Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GRK2 | P25098 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.36 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.36 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.36 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8895764 | 0.90 | TBXA2R (0.42) | IDO1EGFRERBB2KDM4EALDH1A1 | |
| SCHEMBL8897202 | 0.89 | TBXAS1 (0.42) | IDO1EGFRERBB2PPARGKDM4E | |
| SCHEMBL8895561 | 0.89 | TBXAS1 (0.42) | IDO1EGFRERBB2PPARGKDM4E | |
| SCHEMBL8897249 | 0.88 | IDO1 (0.49) | IDO1EGFRERBB2GRK2PPARG | |
| SCHEMBL8894976 | 0.87 | TBXA2R (0.42) | IDO1EGFRERBB2KDM4EALDH1A1 | |
| SCHEMBL8896977 | 0.86 | TBXA2R (0.41) | IDO1KDM4EALDH1A1MMP1MMP13 | |
| SCHEMBL8896692 | 0.85 | TBXA2R (0.43) | IDO1EGFRERBB2EPHX2KDM4E | |
| SCHEMBL8896800 | 0.83 | IDO1 (0.46) | IDO1EGFRERBB2RAB9AKDM4E | |
| SCHEMBL8895621 | 0.82 | IDO1 (0.45) | IDO1EGFRERBB2PPARGKDM4E | |
| SCHEMBL8897644 | 0.81 | GAA (0.41) | ALDH1A1GAASMN1; SMN2POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |