Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194389 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL10631510 | 0.81 | MCL1 (0.44) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL10476199 | 0.79 | USP2 (0.65) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL7049109 | 0.78 | CASP2 (0.46) | KMT2AUSP2MEN1TP53SMN1; SMN2 | |
| SCHEMBL3831548 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL1399147 | 0.76 | USP2 (0.60) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL9188242 | 0.75 | CASP2 (0.56) | FAAH | |
| SCHEMBL22693786 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL8895535 | 0.74 | USP2 (1.00) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL3871043 | 0.74 | USP2 (1.00) | ALDH1A1KMT2AUSP2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618842-A | TREATING DERMATOLOGIC, OPTHALMIC, MUCOSAL, ARTICULAR, CONNECTIVE TISSUE, NERVOUS SYSTEM, ALLERGIC, INFLAMMATORY PATHOLOGIES | LIFEGROUP S.P.A. (IT) | 1997-04-08 | — | — | US | disclosed |