SCHEMBL8895680

SCHEMBL8895680

CCCC(=O)CC(CCC)CCC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HDAC1 Q13547 5/20 0.39
HDAC2 Q92769 5/20 0.39
CHRM1 P11229 1/20 0.39
AKR1A1 P14550 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
HRH1 P35367 1/20 0.39
DRD3 P35462 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HDAC8 Q9BY41 5/20 0.38
HDAC3 O15379 4/20 0.38
FFAR3 O14843 3/20 0.38
TSHR P16473 3/20 0.37
CYP3A4 P08684 2/20 0.37
NFKB1 P19838 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20838328 0.91 CA2 (0.39) CES2CES1HDAC1HDAC2CHRM1
SCHEMBL22110985 0.86 TDP1 (0.32) CES2CES1HDAC1HDAC2CHRM1
SCHEMBL22111104 0.83 TDP1 (0.33) CES2CES1HDAC1HDAC2CHRM1
SCHEMBL20838320 0.82 CES2 (0.41) CES2CES1HDAC1HDAC2TDP1
SCHEMBL28311158 0.82 CES2 (0.41) CES2CES1HDAC1HDAC2TDP1
SCHEMBL12559017 0.78 CYP2C19 (0.43) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL6064456 0.78 TRPV1 (0.44) CES2CES1HDAC1HDAC2CHRM1
SCHEMBL8896681 0.78 TSHR (0.44) CES2CES1HDAC1HDAC2CHRM1
SCHEMBL11475343 0.78 CA2 (0.55) TDP1TSHRCYP3A4ALDH1A1CA2
SCHEMBL2991348 0.78 KMT2A (0.52) CES2CES1TDP1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed