Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22111104 | 0.94 | TDP1 (0.33) | TDP1ALDH1A1CA2CHRM1AKR1A1 | |
| SCHEMBL23438040 | 0.92 | TDP1 (0.35) | TDP1ALDH1A1CA2CHRM1AKR1A1 | |
| SCHEMBL8895680 | 0.86 | CES2 (0.39) | TDP1ALDH1A1CA2CHRM1AKR1A1 | |
| SCHEMBL23438068 | 0.84 | ALDH1A1 (0.31) | TDP1ALDH1A1CA2 | |
| SCHEMBL8897159 | 0.82 | TDP1 (0.43) | TDP1ALDH1A1CA2CHRM1AKR1A1 | |
| SCHEMBL22110898 | 0.82 | CA2 (0.33) | TDP1CA2 | |
| SCHEMBL27441527 | 0.81 | KDM4E (0.41) | — | |
| SCHEMBL27441303 | 0.80 | — | — | |
| SCHEMBL26524377 | 0.79 | ALDH1A1 (0.33) | TDP1ALDH1A1 | |
| SCHEMBL20838328 | 0.78 | CA2 (0.39) | TDP1ALDH1A1CA2CHRM1AKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666802-A1 | METHOD FOR PRODUCING PURIFIED POLYTETRAFLUOROETHYLENE AQUEOUS DISPERSION LIQUID, METHOD FOR PRODUCING MODIFIED POLYTETRAFLUOROETHYLENE POWDER, METHOD FOR PRODUCING POLYTETRAFLUOROETHYLENE MOLDED BODY, AND COMPOSITION | Daikin Industries, Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |