Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.46 |
| ▸ | NOS1 | P29475 | 6/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PAH | P00439 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765227 | 0.82 | HPRT1 (0.47) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL7253844 | 0.78 | KDM4E (0.45) | HPRT1KDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL2787048 | 0.78 | HPRT1 (0.50) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL8537089 | 0.75 | HPRT1 (0.45) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL3743947 | 0.74 | HPRT1 (0.56) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL9739844 | 0.74 | HPRT1 (0.60) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL1672180 | 0.74 | HPRT1 (0.56) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL7209509 | 0.72 | HPRT1 (0.44) | HPRT1NOS1CASP7HSD17B10USP2 | |
| SCHEMBL21637016 | 0.72 | HPRT1 (0.57) | HPRT1NOS1NOS3NOS2 | |
| SCHEMBL9364441 | 0.72 | HPRT1 (0.60) | HPRT1NOS1CASP7HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691307-A | ANTITUMOR AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-11-25 | — | — | US | claimed |