Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.50 |
| ▸ | NOS1 | P29475 | 5/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PAH | P00439 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycidol SCHEMBL7503069 | 0.84 | HPRT1 (0.51) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL8537089 | 0.80 | HPRT1 (0.45) | HPRT1NOS1PNPUSP2CASP7 | |
| SCHEMBL9364441 | 0.80 | HPRT1 (0.60) | HPRT1NOS1PNPUSP2CASP7 | |
| SCHEMBL20849726 | 0.79 | HPRT1 (0.33) | HPRT1 | |
| SCHEMBL3743947 | 0.79 | HPRT1 (0.56) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL8896087 | 0.78 | HPRT1 (0.46) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL23027363 | 0.77 | TYMS (0.35) | HPRT1 | |
| SCHEMBL21637016 | 0.77 | HPRT1 (0.57) | HPRT1NOS1PNPNOS3NOS2 | |
| SCHEMBL9583636 | 0.76 | HPRT1 (0.44) | HPRT1NOS1USP2CASP7HSD17B10 | |
| SCHEMBL9739844 | 0.76 | HPRT1 (0.60) | HPRT1NOS1PNPUSP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117821287-A | Strain for specifically degrading 9-methylguanine and screening method thereof | 安徽大学 | 2024-04-05 | — | — | CN | claimed |
| EP-2196222-A1 | Tricarbonyl complexes of rhenium and technetium comprising amino acids as bidentate ligands and their use as radiotherapeutic chemotoxic agents. | Universität Zürich (CH) | 2010-06-16 | — | — | EP | claimed |
| US-20070071672-A1 | Use of metal tricarbonyl complexes as radiotherapeutic chemotoxic agents | ALBERTO ROGER | 2007-03-29 | — | — | US | claimed |
| CN-1882365-A | Use of metal tricarbonyl complexes as radiotherapeutic chemotoxic agents | UNIV ZUERICH (CH) | 2006-12-20 | — | — | CN | claimed |
| EP-1675626-A2 | USE OF METAL TRICARBONYL COMPLEXES AS RADIOTHERAPEUTIC CHEMOTOXIC AGENTS | Universität Zürich (CH) | 2006-07-05 | — | — | EP | claimed |
| WO-2005039648-A2 | USE OF METAL TRICARBONYL COMPLEXES AS RADIOTHERAPEUTIC CHEMOTOXIC AGENTS | Universität Zürich (CH) | 2005-05-06 | — | — | WO | claimed |
| EP-4689108-A1 | SMAD7 INHIBITORY ANTISENSE OLIGONUCLEOTIDES (ASO) FOR TREATING POUCHITIS AND METHODS OF USING THE SAME | Nogra Pharma Limited (IE) | 2026-02-11 | — | — | EP | disclosed |
| CN-117821287-B | Strain for specifically degrading 9-methylguanine and screening method thereof | 安徽大学 | 2026-02-03 | — | — | CN | disclosed |
| CN-117821287-B | Strain for specifically degrading 9-methylguanine and screening method thereof | 安徽大学 | 2026-02-03 | — | — | CN | disclosed |
| EP-4479034-A1 | CAPSAICIN DERIVATIVES AS BIOENHANCERS ON ACTIVE SUBSTANCES METABOLIZED BY CYP1A2 AND CYP2D6 | aXichem AB (SE) | 2024-12-25 | — | — | EP | disclosed |
| CN-119053326-A | Capsaicin derivatives as bioenhancers of active substances metabolized by CYP1A2 and CYP2D6 | 艾克西化学公司 | 2024-11-29 | — | — | CN | disclosed |
| WO-2024200594-A1 | SMAD7 INHIBITORY ANTISENSE OLIGONUCLEOTIDES (ASO) FOR TREATING POUCHITIS AND METHODS OF USING THE SAME | NOGRA PHARMA LIMITED (IE) | 2024-10-03 | — | — | WO | disclosed |
| CN-117821287-A | Strain for specifically degrading 9-methylguanine and screening method thereof | 安徽大学 | 2024-04-05 | — | — | CN | disclosed |
| US-5773424-A | PARASITICIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0755255-A1 | TREATMENT OF TOXOPLASMOSIS | UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996018398-A1 | TREATMENT OF TOXOPLASMOSIS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-06-20 | — | — | WO | disclosed |
| EP-0464112-B1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | GEA FARMACEUTISK FABRIK AS (DK) | 1994-10-05 | — | — | EP | disclosed |
| US-5223619-A | Catalytic cyclization | A/S GEA FARMACEUTISK FABRIK (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0464112-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS. | GEA FARMACEUTISK FABRIK AS (DK) | 1992-01-08 | — | — | EP | disclosed |
| WO-1990011283-A1 | A PROCESS FOR THE PREPARATION OF 9-SUBSTITUTED GUANINE DERIVATIVES AND INTERMEDIATES FOR USE IN THE PROCESS | A/S GEA FARMACEUTISK FABRIK (DK) | 1990-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070071672-A1 | Use of metal tricarbonyl complexes as radiotherapeutic chemotoxic agents | TOP2B, TK2, MLX | HPRT1 562/4885NOS1 4363/4885PNP 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.