Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896413 | 0.92 | ALDH1A1 (0.45) | ALDH1A1ATML3MBTL1MMP2MMP9 | |
| SCHEMBL8895038 | 0.91 | UTS2R (0.45) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8897043 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ATML3MBTL1POLBMMP2 | |
| SCHEMBL8895380 | 0.90 | IDO1 (0.50) | ALDH1A1ATML3MBTL1POLBMMP2 | |
| SCHEMBL8898350 | 0.90 | ALDH1A1 (0.48) | ALDH1A1ATML3MBTL1MMP2MMP9 | |
| SCHEMBL8894981 | 0.89 | FFAR1 (0.48) | ALDH1A1ATML3MBTL1POLBMMP2 | |
| SCHEMBL8897514 | 0.89 | NPSR1 (0.42) | ALDH1A1ATML3MBTL1POLBMMP2 | |
| SCHEMBL8896101 | 0.88 | FFAR1 (0.47) | ALDH1A1ATML3MBTL1POLBLMNA | |
| SCHEMBL8895376 | 0.88 | SIGMAR1 (0.41) | ALDH1A1ATML3MBTL1POLBMMP2 | |
| SCHEMBL8895525 | 0.88 | SIGMAR1 (0.41) | ALDH1A1ATML3MBTL1POLBMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597848-A | PLATELET AGGREGATION INHIBITORS, ANTITHROMBOTIC AGENTS, ANTIASTHMATIC AGENTS, ANTIALLERGIC AGENTS | HOKURIKU SEIYAKU CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0663392-A1 | BENZENESULFONAMIDE DERIVATIVE AND USE THEREOF | HOKURIKU SEIYAKU CO., LTD. (JP) | 1995-07-19 | — | — | EP | disclosed |